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Visine Allergy (Levocabastine) 0.05% 4ml
Visine Allergy (Levocabastine) 0.05% 4ml
Product Code: 208252 Famar

Visine Allergy (Levocabastine) 0.05% 4ml

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$13.20 Price in points: 58

pharmachologic effect

Allergy drug, a selective blocker of histamine long-acting H1-receptors. Local effect occurs within 5 min. Vizin® Alerdzhi eliminates the typical symptoms of allergic conjunctivitis (itching, redness, swelling of the conjunctiva and eyelids, watery eyes).

The action continues until 12 hours.


Absorption and distribution

After instillation in the eye in a dose of 15 mcg / drop absorbed about 6 micrograms levocabastine. Cmax plasma levels achieved after about 6 hours.

levocabastine binding to plasma proteins is approximately 55%.

Metabolism and excretion

The main metabolite of levocabastine, atsilglyukuronid, formed by glucuronidation, which is the main by the formation of metabolites.

T1 / 2 levocabastine is 39-70 hours. Levocabastine appears mainly kidneys unchanged (about 70% of the absorbed amount).


Allergic conjunctivitis.


  • Wearing contact lenses.
  • Lactation (breastfeeding).
  • Children under 12 years old.
  • Hypersensitivity to the drug.


  • Elderly patients.
  • Impaired renal function.

Pregnancy and breast-feeding

There are no data on the use of levocabastine in pregnant women. Therefore it is not recommended to use eye drops Alerdzhi Vizin® during pregnancy, except in cases where the expected benefit of therapy to the mother outweighs the potential risk to the fetus.

Levocabastine is excreted in breast milk, so breast-feeding should be discontinued, if necessary, use during lactation.

In preclinical animal studies levocabastine when administered systemically in doses up to 2,500 times (in terms of mg / kg) above the recommended maximum dosage for topical application in humans caused no embryotoxic and teratogenic effects. In animals when administered systemically in doses levocabastine, more than 5,000 times (in terms of mg / kg) exceeding the maximum recommended dose for topical application in humans, marked teratogenic properties and / or increase in embryo death.

special instructions

During the period of treatment is not recommended to use a soft (hydrophilic) contact lenses - possible interaction with the drug included in the benzalkonium chloride.

To prevent microbial contamination should avoid touching the pipette century and tightly close the bottle.

The patient should be informed that if the drug has come into disrepair or expiration date, you should not throw it in the waste water or the street. It is necessary to put the drug in the bag and put in the trash. These measures will help to protect the environment.

Use in children

Do not use this in children under the age of 12 years.

Use in impaired renal function

The caution with impaired renal function.

Effects on ability to drive vehicles and management mechanisms

Eye drops Visine Alerdzhi not affect the speed of psychomotor reactions. The drug may be used, patients are engaged in driving a car or operate machinery.


Active substance: levocabastine hydrochloride (0.54 mg / ml) based on levocabastine 0.5 mg / ml (0.05%)

Excipients: propylene 48.26 uL, 8.66 mg disodium hydrogen phosphate, sodium dihydrogen phosphate monohydrate 5.38 mg hypromellose (2910 mPa.s 3) 2.50 mg Polysorbate 80 1.00 mg Benzalkonium chloride 0.15 mg (as a 50% solution 0.03 mL) disodium edetate 0.15 mg water for injection to 1.0 ml.

Dosing and Administration

Applied locally.

For adults and children over 12 years: 1 drop in each eye 2 times / day, if necessary - 3-4 times / day. Treatment should be continued until symptoms disappear.

Since eye drops are Vizin® Alerdzhi suspension before each use vial should be shaken.

Using a dropper bottle

Remove the cap from the dropper bottle and turn the bottle.

Do not touch the tip of the bottle any surfaces.

After applying to screw cap dropper bottle.

Side effects

From a sight organ: often - in the field of eye pain, blurred vision, rarely - swelling of the eyelids, the frequency is unknown - conjunctivitis, blepharitis, eye redness, burning sensation, itching, watery eyes.

Systemic reactions: the frequency is unknown - angioneurotic edema, allergic reactions, contact dermatitis, urticaria, often - headache.


Symptoms: In case of accidental ingestion may decrease blood pressure, tachycardia, severe sedation.

Treatment: forced diuresis.

Storage conditions

Store at temperatures not above 25 ° C.

Shelf life

2 years. Opened vial 1 month.