It is a mixture of several antibiotics produced by Micromonospora purpurea. Sterile solution, 1 ml of which contains 40 mg of the active substance.
Do not use gentamicin simultaneously or sequentially with other ototoxic and nephrotoxic drugs (streptomycin, kanamycin, neomycin). Do not use the drug in patients with severe renal dysfunction.
Ototoxic and nephrotoxic effects
Dosage and administration
Gentamicin solution is administered intramuscularly or orally twice a day at 10-12 hour intervals in the following dosages:
Horses: Intramuscularly 2.5 mg/kg for 3-5 days
Cattle: Intramuscularly 3 mg/kg for 3-5 days
Oral 8mg/kg 3-5 days
Pigs: Intramuscularly, 4 mg/kg 1-3 days
Oral 6mg/kg 3-5 days
Dogs, cats: Intramuscularly 2.5 mg/kg 3-7 days.
Gentamicin has a broad spectrum of antimicrobial action. It is active against most gram-negative and gram-positive microorganisms, including Proteus, Escherichia, Salmonella and Staphylococcus aureus.
The antibiotic has no effect on anaerobic bacteria, fungi, viruses and protozoa.
When administered intramuscularly, the drug penetrates well into many organs and tissues. Maximum concentration in blood is reached 1 hour after injection.
After single injection the therapeutic concentration of the antibiotic in the body is maintained for 8-12 hours after injection.
When administered orally the drug is practically not absorbed from the gastrointestinal tract and exerts its effect only in the intestine for 12 hours.
When parenteral administration of gentamicin the antibiotic is excreted unchanged in the body mainly with urine, and when administered orally - with the feces.
Slaughter of animals for meat shall be allowed 21 days after the last drug administration. Milk obtained from animals treated with gentamicin shall not be used for food purposes during treatment and within 72 hours after cessation of the drug administration.
Conditions of storage
List B. Store in a dry place protected from light at 5 - 25 °С. Shelf life - 2 years.
solution for injection