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Detralex 500 mg N30 tabs
Detralex 500 mg N30 tabs
Product Code: 859

Detralex 500 mg N30 tabs

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$27.46
16
Description

Latin name

Detralex

Release form

Pills

Packaging

30 pcs.

pharmachologic effect

Detralex has venotonic and angioprotective properties.

The drug reduces the distensibility of veins and venous stasis, reduces capillary permeability and increases their resistance.

The results of clinical studies confirm the pharmacological activity of the drug in relation to the parameters of venous hemodynamics.

The statistically significant dose-dependent effect of Detralex was demonstrated for the following venous plethysmographic parameters: venous capacity, venous extensibility, and venous emptying time.

The optimal dose / effect ratio is observed when taking 2 tablets.

Detralex increases venous tone: with the help of venous occlusive plethysmography, a decrease in the time of venous emptying has been shown.

In patients with signs of severe microcirculation disorders, there is (statistically significant), compared with placebo, an increase in capillary resistance, assessed by angiostereometry, after therapy with Detralex.

The therapeutic efficacy of Detralex has been proven in the treatment of chronic diseases of the veins of the lower extremities, as well as in the treatment of hemorrhoids.

Pharmacokinetics

The main excretion of the drug occurs in the feces.

With urine, on average, about 14% of the taken amount of the drug is excreted.

T1 / 2 is 11 hours.

The drug undergoes active metabolism, as evidenced by the presence of phenolic acids in the urine.

Indications

Symptomatic therapy of venous lymphatic insufficiency, feeling of heaviness in the legs, pain, morning fatigue" of the legs, convulsions, trophic disorders, symptomatic therapy of exacerbation of hemorrhoids.

Contraindications

Hypersensitivity to drug components.

Application during pregnancy and lactation

Pregnancy

Animal experiments have not revealed teratogenic effects.

Until now, there have been no reports of any side effects when using the drug by pregnant women.

Lactation

Due to the lack of data on the excretion of the drug into breast milk, lactating women are not recommended to take the drug.

special instructions

In case of exacerbation of hemorrhoids, the appointment of this drug does not replace the specific treatment of other anal disorders.

The duration of treatment should not exceed the recommended period.

In the event that the symptoms do not disappear after a short therapy, a proctological examination should be performed and the ongoing therapy should be reviewed.

In the presence of venous circulation disorders, the maximum effect of treatment is provided by a combination with a healthy, well-balanced lifestyle, in which it is desirable to avoid prolonged exposure to the sun, reduce body weight, go for walks and in some cases wear special socks that improve blood circulation.

Influence on the ability to drive vehicles and use mechanisms

The drug does not affect the ability to drive vehicles and perform work that requires a high speed of psychomotor reactions.

Structure

1 tablet contains:

Active ingredients: purified micronized flavonoid fraction 500 mg (including diosmin (90%) 450 mg, flavonoids, expressed as hesperidin (10%) 50 mg)

Excipients: gelatin, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, talc, glycerol, macrogol 6000, hydroxypropyl methylcellulose, iron oxide yellow (E172), iron oxide red (E172), titanium dioxide (E171), sodium lauryl sulfate.

Method of administration and dosage

The drug is taken orally.

The recommended dose is 2 tablets per day, 1 tablet in the middle of the day and 1 tablet in the evening with meals.

In the period of exacerbation of hemorrhoids - 6 tablets per day for 4 days, then 4 tablets per day for the next 3 days.

Side effects

From side

Name ENG

DETRALEX

Clinical and pharmacological group

Venotonic and venoprotective drug

ATX code

Diosmin in combination with other drugs

Dosage

500mg

Structure

1 tablet contains: Active ingredients: purified micronized flavonoid fraction 500 mg (including diosmin (90%) 450 mg, flavonoids, expressed as hesperidin (10%) 50 mg)

...

Excipients: gelatin, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, talc, glycerol, macrogol 6000, hydroxypropyl methylcellulose, iron oxide yellow (E172), iron oxide red (E172), titanium dioxide (E171), sodium lauryl sulfate.

Indications

Symptomatic therapy of venous lymphatic insufficiency, feeling of heaviness in the legs, pain, "morning fatigue" of the legs, convulsions, trophic disorders, symptomatic therapy of exacerbation of hemorrhoids.

Storage conditions and periods

At a temperature not higher than 30 degrees.

Expiration date: 4 years

INN / Active ingredient

Hesperidin, Diosmin

Contraindications

Hypersensitivity to drug components.

Specifications

Category

Diseases of the veins

Scope of the drug

Heart, vessels, blood

Release form

Tablet

Manufacturer country

Russia

Package quantity, pcs

thirty

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Servier

The amount of the dosage form in the primary package

15 pcs.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Venotonic and venoprotective agent

Anatomical and therapeutic characteristics

C05CA53 Diosmin, in combination with other drugs

Dosage form

Film-coated tablets

Expiration date in days

1460

Dosage (volume) of the substance in the preparation

500 mg + 50 mg

Package weight, g

35

Mode of application

:

The drug is taken orally.

< br> < br> The recommended dose is 2 tablets per day, 1 tablet - in the middle of the day and 1 tablet - in the evening during meals.

< br> < br> During the period of exacerbation of hemorrhoids - 6 tablets per day for 4 days, then 4 tablets per day for the next 3 days.

Information on technical characteristics, delivery set, country of manufacture "