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Gastal tablets N60
Gastal tablets N60
Product Code: 834

Gastal tablets N60

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$19.38
16
Gastal tablets, # 60

  • heartburn (after taking medicines, alcohol, coffee; inaccuracies in absorption, abuse of nicotine, etc.);

  • conditions accompanied by increased acid production: gastritis, gastric ulcer and duodenal ulcer;

  • symptomatic ulcers of various origins;

  • erosion of the gastric mucosa and upper gastrointestinal tract;

  • reflux esophagitis;

  • hernia of the esophageal opening of the diaphragm;

  • acute pancreatitis, exacerbation of chronic pancreatitis (as part of combination therapy);

  • fermentative or putrid dyspepsia (as part of combination therapy).

Inside. The tablet should be gradually dissolved (not swallowed whole).

Adults are recommended to take 1-2 tablets 1 hour after meals and before bedtime. 4-6 times / day, but no more than 8 tab. within 24 hours

The duration of taking Gastal should not exceed 2 weeks.

For prophylaxis, Gastal is used before the alleged irritant effect on the gastrointestinal mucosa.

Similar doses are recommended for heartburn, regardless of food intake.

For children aged 6-12 years , half of the adult dose is recommended.

Active ingredients:

aluminum hydroxide-magnesium carbonate gel - 450 mg

magnesium hydroxide - 300 mg

Excipients : lactose monohydrate - 111.5 mg, mannitol - 110 mg, pregelatinized starch - 32 mg, colloidal silicon dioxide - 2 mg, croscarmellose sodium type A - 50 mg, aspartame - 2.5 mg, magnesium stearate - 6 mg, mint flavor 11890- 71 - 6 mg.

  • chronic renal failure;

  • Alzheimer's disease;

  • hypophosphatemia;

  • children under 6 years of age;

  • hypersensitivity.

With care : children under 12 years of age; during lactation and during pregnancy - only by appointment and under the supervision of a doctor.

Lozenges (mint) white or almost white, round with a smooth surface and a bevel, with a mint taste.

Composition:

Active ingredients:

aluminum hydroxide-magnesium carbonate gel - 450 mg

magnesium hydroxide - 300 mg

Excipients : lactose monohydrate - 111.5 mg, mannitol - 110 mg, pregelatinized starch - 32 mg, colloidal silicon dioxide - 2 mg, croscarmellose sodium type A - 50 mg, aspartame - 2.5 mg, magnesium stearate - 6 mg, mint flavor 11890- 71 - 6 mg.

Lozenges (cherry), white or almost white, round, with a smooth surface and a bevel, with a cherry flavor.

Composition:

Active ingredients:

aluminum hydroxide-magnesium carbonate gel - 450 mg

magnesium hydroxide - 300 mg

Excipients : lactose monohydrate - 112 mg, mannitol - 112 mg, pregelatinized starch - 32 mg, colloidal silicon dioxide - 2 mg, croscarmellose sodium type A - 50 mg, aspartame - 2 mg, magnesium stearate - 6 mg, cherry flavor E9407963 - 4 mg.

Lozenges (cherry), white or almost white, round, with a smooth surface and a bevel, with a cherry flavor.

Composition:

Active ingredients:

aluminum hydroxide-magnesium carbonate gel - 450 mg

magnesium hydroxide - 300 mg

Excipients : lactose monohydrate - 112 mg, mannitol - 112 mg, pregelatinized starch - 32 mg, colloidal silicon dioxide - 2 mg, croscarmellose sodium type A - 50 mg, aspartame - 2 mg, magnesium stearate - 6 mg, orange flavor 1013042 - 4 mg

Clinical and pharmacological group: Antacid drug

Pharmaco-therapeutic group: Antacid

pharmachologic effect

Gastal is a combined oral antacid drug. Reduces the increased acidity of gastric juice to the physiological level and eliminates dyspeptic disorders by neutralizing excess hydrochloric acid in the stomach. Magnesium hydroxide and aluminum hydroxide, which are part of Gastal, provide fast and long-term neutralization, resulting in an antacid effect.

The antacid effect of the drug manifests itself immediately after taking the Gastal tablets and lasts about 2 hours. 1 Gastal tablet neutralizes about 21.5 mmol of hydrochloric acid. Gastal inhibits the action of pepsin, lysolecithin and bile acids, thus also eliminating gastric dysfunction.

Gastal, in addition to the antacid effect, activates protective and regenerative mechanisms in the gastric mucosa. The cytoprotective effect caused by aluminum ions includes the stimulation of the secretion of mucus and sodium bicarbonate in the stomach, the accumulation of epidermal growth factor in the lesion focus, an increase in the concentration of phospholipids in the stomach, and other mechanisms.

Pharmacokinetics

Gastal has no systemic effect in patients with normal renal function.

After interaction with hydrochloric acid of gastric juice, aluminum hydroxide reacts with phosphates and carbonates in the alkaline medium of the intestine and is excreted in the feces in the form of insoluble salts. Magnesium hydroxide reacts with hydrochloric acid in gastric juice to form magnesium chloride, which has an osmotic laxative effect in the small intestine. Magnesium is also excreted in the feces as insoluble carbonate.

Indications

  • heartburn (after taking medicines, alcohol, coffee; inaccuracies in absorption, abuse of nicotine, etc.);

  • conditions accompanied by increased acid production: gastritis, gastric ulcer and duodenal ulcer;

  • symptomatic ulcers of various origins;

  • erosion of the gastric mucosa and upper gastrointestinal tract;

  • reflux esophagitis;

  • hernia of the esophageal opening of the diaphragm;

  • acute pancreatitis, exacerbation of chronic pancreatitis (as part of combination therapy);

  • fermentative or putrid dyspepsia (as part of combination therapy).

Dosage regimen

Inside. The tablet should be gradually dissolved (not swallowed whole).

Adults are recommended to take 1-2 tablets 1 hour after meals and before bedtime. 4-6 times / day, but no more than 8 tab. within 24 hours

The duration of taking Gastal should not exceed 2 weeks.

For prophylaxis, Gastal is used before the alleged irritant effect on the gastrointestinal mucosa.

Similar doses are recommended for heartburn, regardless of food intake.

For children aged 6-12 years , half of the adult dose is recommended.

Side effect

Rarely : allergic reactions, nausea, vomiting, changes in taste, diarrhea, constipation.

Contraindications for use

  • chronic renal failure;

  • Alzheimer's disease;

  • hypophosphatemia;

  • children under 6 years of age;

  • hypersensitivity.

With care : children under 12 years of age; during lactation and during pregnancy - only by appointment and under the supervision of a doctor.

Application during pregnancy and lactation

As with the appointment of all other drugs, the use of Gastal during pregnancy is possible only in special cases and only on the recommendation of a doctor.

Application for impaired renal function

Patients with impaired renal function are not recommended to use Gastal for a longer period and in higher doses than recommended.

Application in children

With care : children under 12 years of age. Contraindication: children under 6 years of age.

special instructions

For patients with low body weight and children, smaller doses are used and for a shorter period of time.

Patients with impaired renal function are not recommended to use Gastal for a longer period and in higher doses than recommended.

Continuous intake for more than 2 weeks - only after consulting a doctor.

Overdose

There were no symptoms of acute overdose.

With prolonged use in high doses of drugs containing aluminum and magnesium, hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesemia and hyperaluminaemia, encephalopathy, nephrocalcinosis and renal dysfunction may develop. Possible increased side effects from the gastrointestinal tract (constipation, diarrhea). In patients with concomitant renal failure, thirst, decreased blood pressure, hyporeflexia.

When these symptoms appear, symptomatic treatment should be carried out.

Drug interactions

The interval between taking Gastal and other medicines should be 1-2 hours.

Gastal enhances the activity of levodopa and nalidixic acid; reduces and slows down the absorption of tetracycline antibiotics, ciproflocacin and ofloxacin, salicylates, isoniazid, naproxen, iron preparations, cardiac gpicosides, indomethacin, aminazine, phenytoin, H2-histamine receptor blockers, beta-adreblockers, difluranizal. M-anticholinergics, slowing down gastric emptying, enhance and lengthen the effect of the drug.

Storage conditions

Store at a temperature not exceeding 25 ? C.

Shelf life

Shelf life is 3 years. Do not use after the expiration date.

Terms of sale

The drug is approved for use as a means of OTC.

Contacts for inquiries

TEVA (Israel)