Nurofen express gel 5%
Tube 50 g.
Pharmacotherapeutic group: non-steroidal anti-inflammatory drug (NSAID).
ATX code: М02AA13
The drug Nurofen Express in the dosage form of a gel for external use is easy to apply and quickly absorbed into the skin.
Pharmacodynamics: The drug belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs).
It has a double effect: analgesic and anti-inflammatory.
Ibuprofen, being a propionic acid derivative, indiscriminately blocks cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2), as a result of which it inhibits the synthesis of prostaglandins - mediators of pain, inflammation and hyperthermic reaction.
When applied to the skin, the gel has an additional cooling effect due to the rapid evaporation of benzyl alcohol contained in the composition.
Pharmacokinetics: After application to the skin, ibuprofen is found in the epidermis and dermis after 24 hours.
The maximum plasma concentration of ibuprofen when applied topically is 5% of the maximum concentration when using oral ibuprofen.
There is practically no clinically significant systemic absorption.
It is metabolized in the liver.
It is excreted by the kidneys (not more than 1% unchanged) and, to a lesser extent, with bile.
As a topical analgesic and anti-inflammatory agent for conditions such as muscle pain, back pain, arthritis, pain from ligament injuries and sprains, sports injuries and neuralgia.
- Hypersensitivity to ibuprofen or other components that make up the drug.
- A history of hypersensitivity reactions (bronchial asthma, rhinitis, Quincke's edema, urticaria) in response to the use of acetylsalicylic acid or other NSAIDs.
- Violations of the integrity of the skin at the site of application of the drug (including infected abrasions and wounds, weeping dermatitis, eczema).
- Children under 14 years of age.
- Pregnancy III trimester.
If you have the conditions listed in this section, you should consult a doctor before using the drug.
Bronchial asthma or allergic diseases in the stage of exacerbation or in history - the development of bronchospasm, renal failure, liver failure, gastric ulcer, including a history of enteritis, colitis, hemorrhagic diathesis, pregnancy I-II trimester, period of breastfeeding is possible.
Application during pregnancy and lactation
The use of the drug in the third trimester of pregnancy is contraindicated.
Avoid the use of the drug in the I-II trimesters of pregnancy, if necessary, the use of the drug should be consulted with a doctor.
There is evidence that small amounts of ibuprofen can pass into breast milk without any negative consequences for the health of the infant, therefore, usually with short-term use, there is no need to stop breastfeeding.
If you need to use the drug for a long time, you should consult a doctor to decide whether to stop breastfeeding for the period of using the drug.
Avoid contact with eyes, lips and other mucous membranes, damaged skin.
Do not use in combination with an occlusive (sealed) medical dressing.
Avoid excessive exposure to sunlight on the area of application of the drug.
Influence on the ability to drive vehicles, mechanisms
It does not affect activities requiring increased concentration of attention and speed of psychomotor reactions (driving vehicles or operating mechanisms).
100 g of gel contains active substance: ibuprofen 5 g and excipients: hyethylose
Clinical and pharmacological group
NSAIDs for external use
5% x 50g
100 g of gel contains the active substance: ibuprofen 5 g and excipients: hyethylose 1.8 g, sodium hydroxide QS (0.93 - 1 g), benzyl alcohol 1 g, isopropanol 5 g, purified water 86.2 g.
INN / Active ingredient
Storage conditions and periods
At a temperature not higher than 25 degrees.
Expiration date: 3 years
Scope of the medicinal product
Package quantity, pcs
Minimum age from
14 years old
Way of introduction
The amount of the dosage form in the primary package
Primary packaging type
Type of consumer packaging
Anatomical and therapeutic characteristics
Gel for external use
Dosage (volume) of the substance in the preparation
The target audience
Expiration date in days
Package weight, g
Mode of application
For external use only. < br> < br> Carefully read the instructions before using the drug. < br> < br> Nurofen Express gel is prescribed for adults and children over 14 years old. < br> < br> When using the tube for the first time: open the cap, check that the protective foil on the neck of the tube is not damaged. Open the foil by pressing with the outside of the lid. < br> < br> Squeeze 4-10 cm of the preparation (equivalent to approximately 50-125 mg ibuprofen) from the tube onto your hand and gently massage the gel into the skin until completely absorbed. < br> < br > Wash your hands immediately after using the drug. < br> < br> Reuse the drug no earlier than after 4 hours. The gel should not be applied more than four times in 24 hours. The maximum daily dose is 500 mg. < br> < br> If symptoms persist or worsen within 2 weeks of using the drug, you must stop treatment and consult a doctor. < br> < br> Do not exceed the indicated dose.
Information on technical characteristics, delivery set, country of manufacture