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Klarisens (Loratadine) 10mg N10
Klarisens (Loratadine) 10mg N10
Product Code: 208237 Pharmstandart

Klarisens (Loratadine) 10mg N10

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$3.50 Price in points: 43
50

Expiration date: 06/2020 

Structure and Composition:

5 ml of syrup contains 5 mg loratadine, in dark glass bottles of 100 ml, in a cardboard bundle one bottle complete with measuring spoon of 5 ml and 2.5 ml.

1 tablet - 10 mg in blisters of 10 pieces.

Characteristic:

Colorless or yellowish liquid with a fruity odor may be the presence of bubbles Tablets white or nearly white.

Pharmachologic effect:

Blocker II generation of peripheral H1-histamine receptors. Decreases capillary permeability, has a decongestant and a moderate effect.

Pharmacokinetics:

Rapidly absorbed, binding to plasma proteins - 97%. It does not cross the blood-brain barrier. Cmax achieved after 8-12 hours of T1 / 2 is 3-20 hours, on average, 8.4 hours When biotransformation into active metabolite -.. Deksarboetoksiloratadin. The drug and its metabolites are excreted in the urine and faeces.

Description of the pharmacological actions:

Do not have a sedative effect, it is not addictive.

Clinical Pharmacology:

Action is 30 minutes after the administration and lasts up to 24 hours. In patients with chronic renal insufficiency pharmacokinetics unchanged. In alcoholic liver disease and in the elderly Cmax and T1 / 2 increases.

Testimony:

Allergic rhinitis (seasonal and perennial) and conjunctivitis, acute urticaria, angioedema, allergic reactions to insect bites, itching dermatoses (contact allergodermia, atopic dermatosis, chronic eczema), pseudoallergy reaction.

Contraindications:

Hypersensitivity, phenylketonuria, pregnancy, breast-feeding.

Application of pregnancy and breastfeeding:

Contraindicated. At the time of treatment should stop breastfeeding.

Side effect:

In rare cases - fatigue, headache, dizziness, dyspepsia, nausea, dry mouth, allergic reactions.

Drug Interactions:

Erythromycin, ketoconazole, cimetidine increase the concentration of drug in the blood. Erythromycin Klarisens lowers blood by 15%.

Dosage and administration:

Inside, and food. Adults and children (under 12 years of age or with body weight over 30 kg) - 10 mg (1 tablet or 2 scoops of syrup 5 mL) 1 time per day. Children aged 2 to 12 years - 5 mg (1/2 tablet or 1 measuring spoon of 5 ml of syrup) 1 time per day.

Overdose:

Symptoms: drowsiness, headache, tachycardia.

Treatment: symptomatic.

Precautionary measures:

To apply caution in patients with impaired hepatic function: we recommend taking a day (1 every 2 days).