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Pyobacteriophage polyvalent purified,  vials of 20 ml, 4 pcs.
Pyobacteriophage polyvalent purified,  vials of 20 ml, 4 pcs.
Product Code: bakterio-poly-purified-4x20

Pyobacteriophage polyvalent purified, vials of 20 ml, 4 pcs.

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$20.00
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Composition

Active ingredient: sterile mixture of purified filtrates of phagolysates of bacteria Klebsiella pneumoniae, Klebsiella ozaenae, Klebsiella rhinoscleromatis


pharmachologic effect

The drug causes specific lysis of bacteria Klebsiella pneumoniae, Klebsiella ozaenae, Klebsiella rhinoscleromatis.


Indications

Treatment and prevention of diseases caused by the bacteria Klebsiella pneumoniae, Klebsiella ozaenae, Klebsiella rhinoscleromatis as part of complex therapy:

  • ozena, scleroma;
  • diseases of the gastrointestinal tract (gastroenterocolitis, cholecystitis, pancreatitis, intestinal dysbiosis);
  • inflammatory diseases of newborns and young children (gastroenterocolitis, intestinal dysbiosis, omphalitis, pemphigus, pyoderma, septicemia and septicopyemia of various localization);
  • surgical infections (suppurating wounds, purulent skin lesions, burns, peritonitis, pleurisy, mastitis, osteomyelitis, abscess);
  • urogenital infections (cystitis, pyelonephritis, urethritis, endometritis, vulvitis, bartholinitis, colpitis, salpingoophoritis);
  • inflammatory diseases of the ear, throat, nose, sinuses, mouth, pharynx, larynx, bronchi, lungs and pleura (otitis media, sore throat, pharyngitis, laryngitis, stomatitis, periodontitis, sinusitis, frontal sinusitis, bronchitis, pneumonia, pleurisy);
  • post-traumatic conjunctivitis, keratoconjunctivitis, purulent corneal ulcer and iridocyclitis;
  • prevention of nosocomial infections caused by Klebsiella.

Contraindications

Hypersensitivity to the drug.


Side effects

Allergic reactions.


How to take, the course of administration and dosage

The drug is used for oral administration (through the mouth), in the form of enemas, applications, irrigation, the introduction into the cavity of wounds, vagina, uterus, nose, sinuses, and also drained cavities: abscesses, abdominal, pleural, bladder, renal pelvis.

Inside the drug is taken on an empty stomach 0.5-1 hour before meals.


Age

Dose per reception

with various methods of drug administration

inside

(ml)

in enema

(ml)

0-6 month

5

10

6-12 month

10

20

From 1 year to 3 years

15

20-30

From 3 to 8 years

20

30-40

From 8 years and older

20-30

40-50


Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both locally and taking the drug orally.


In the case of treatment of the cavity of a purulent focus with chemical antiseptics, it must be washed with sterile 0.9% sodium chloride solution before using the bacteriophage.


When treating ozena and scleroma, the drug is used to flush the nasal cavity and upper respiratory tract mucosa, for introduction into the nasal sinuses cavity (according to clinical indications), as well as for the defeat of the pharynx, larynx, and trachea in the form of inhalations (without heating and using ultrasound). The dose of the drug for the treatment of mucous membranes of the nose and upper respiratory tract 10-20 ml. After washing the mucous membranes, turunds moistened with the preparation are injected into each nasal passage by turns into the nasal cavity and left for 1 hour. The procedure is repeated 2-3 times a day for 20-40 days. Since ozena and scleroma are chronic diseases, in order to prevent exacerbations, it is recommended to conduct 20-40 days of treatment once a year according to the above scheme.


In the treatment of angina, pharyngitis, laryngitis, the drug is used to rinse the mouth and pharynx 3 times a day for 10-20 ml, the course of treatment is 7-10 days.


In the treatment of bronchitis, pneumonia is taken orally 3 times a day for 10-20 ml, and also used in the form of aerosols and inhalations (without heating and using ultrasound), the course of treatment is 15-20 days.


In the treatment of otitis media, the drug is used to rinse and inject into the cavity of the middle ear 2–5 ml 1–3 times a day. The course of treatment is 7-15 days.


In the treatment of inflammation of the sinuses of the nose, the drug is used for washing the nasal cavity, nasopharynx and sinuses in a dose of 5-10 ml and injecting 2-3 ml into the sinuses. The procedure is repeated daily once for 7-10 days. In addition, the drug is injected into the nasal cavity in the form of turunds moistened with bacteriophage, in turn in each nasal passage and leave for 0.5-1 hour. The procedure is repeated 3 times a day, the course of treatment is 7-15 days.


In the treatment of stomatitis and chronic periodontitis, the drug is used in the form of mouth rinses 3-4 times a day at a dose of 10-20 ml, as well as the introduction of turunds impregnated with Klebsiella bacteriophage into periodontal pockets for 5-10 minutes, the course of treatment is 7-10 days .


For conjunctivitis and keratoconjunctivitis, the drug is used 2-3 drops 4-5 times a day, the course of treatment is 5-7 days; with purulent corneal ulcer - 4-5 drops per day for 7-10 days; with purulent iridocyclitis, 6–8 drops every 3 hours in combination with ingestion in therapeutic dosages for 7–10 days.


For abscesses after opening and removal of purulent contents, the drug is administered in an amount less than the volume of removed pus once a day, a course of treatment is 7-10 days.


With peritonitis and pleurisy, the drug is injected into the drained cavity - the abdominal and pleural through the drainage tubes once daily 20-70 ml, the course of treatment is 10-15 days.


When osteomyelitis drug is injected into the wound cavity through turunda, drainage in the amount of 10-30 ml once a day, the course of treatment is 15-20 days.


In the treatment of wound suppurations, the drug is used in the form of irrigation, applications, dressings, injections into the drainage at a dose of 5-50 ml, depending on the lesion at least once a day, the course of treatment is 10-15 days.


In the treatment of purulent-inflammatory gynecological diseases (suppuration of wounds, endometritis, vulvitis, Bartholinitis, colpitis, salpingoophoritis), the drug is used for irrigation, applications, injected into the cavity of wounds, vagina, uterus 5-20 ml once a day for 7-10 days


For cystitis, pyelonephritis, urethritis, the drug is taken orally at a therapeutic dose 3 times a day 1 hour before meals for 10-20 days. In that case, if the cavity of the bladder or the renal pelvis is drained, the drug is injected through a cystostom or nephrostomy 1-3 times a day, 20-50 ml into the bladder and 5-7 ml into the renal pelvis, the course of treatment is 7-15 days.


In case of gastroenterocolitis, pancreatitis, cholecystitis, and intestinal dysbiosis, bacteriophage is taken orally in age dosages 3 times a day 1 hour before meals for 7-15 days (for clinical reasons). When indomitable vomiting drug is used in the form of high enemas 2-3 times a day, 20-40 ml. For intestinal dysbiosis, the drug can be used with normoflora preparations.


For the prevention of nosocomial surgical infections, the drug is used to treat postoperative and freshly infected wounds at a dose of 5-50 ml, depending on the lesion, once a day for 5-7 days.


Use of the drug in children under 1 year (including premature babies)


With gastroenterocolitis, pneumonia and sepsis of newborns, the drug is applied through the mouth 2-3 times a day, 3-5 ml for 30 minutes before feeding. In cases of indomitable vomiting, the drug is used in the form of high enemas (through a vapor tube or catheter) once daily in a dose of 5-10 ml. Perhaps a combination of rectal (in the form of high enemas) and oral administration of the drug. The course of treatment is 7-15 days (according to clinical


With gastroenterocolitis, pneumonia and sepsis of newborns, the drug is applied through the mouth 2-3 times a day, 3-5 ml for 30 minutes before feeding. In cases of indomitable vomiting, the drug is used in the form of high enemas (through a vapor tube or catheter) once daily in a dose of 5-10 ml. Perhaps a combination of rectal (in the form of high enemas) and oral administration of the drug. The course of treatment is 7-15 days (according to clinical indications). In case of recurrent course of the disease, repeated courses of treatment are possible.


In order to prevent the onset of nosocomial infections in newborns, the bacteriophage is used according to epidemic indications for 3-5 ml 3 times a day 30 minutes before feeding during the entire hospital stay.


In the treatment of omphalitis, pyoderma, infected wounds, bacteriophage is used in the form of applications of 5-10 ml 2-3 times a day (gauze moistened with bacteriophage and applied to the umbilical wound or the affected skin area) for 7-15 days.


The use of the drug does not preclude the use of other antibacterial and anti-inflammatory drugs.


Special instructions

The opening of the vials and ampoules and the procedure for administering the drug are carried out with strict adherence to the rules of antiseptics. In case of violation of the integrity of the packaging and labeling, clouding of the drug it is not used.


Release form

Oral, topical and external solution


Storage conditions

In a dry, dark place at a temperature of 2–8 ° C

Shelf life

2 years

Active substance

Bacteriophage klebsiella