Composition
Ambroxol hydrochloride 20 mg
sodium glycyrrhizinate 30 mg
Thermopsis dry extract 10 mg
Sodium bicarbonate 200 mg
Excipients: potato starch, microcrystalline cellulose, povidone K25 (Kollidon K25), talc, stearic acid, sodium carboxymethyl starch (sodium starch glycolate, primodzhel).
pharmachologic effect
Combined preparation for the treatment of cough, has mucolytic and expectorant action, and also has anti-inflammatory activity. Action Codelac® Broncho pharmacological properties due to its components.
Ambroxol has sekretomotornym, sekretoliticheskim and expectorant action, normalizes impaired ratio of serous and mucous components of phlegm, increases the secretion of surfactant in the alveoli. It reduces the viscosity of mucus and facilitates its expectoration.
Glitsirrat (glycyrrhizic acid and its salts), anti-inflammatory and antiviral action. It has a cytoprotective effect through antioxidant and membrane stabilizing activity. It potentiates the action of endogenous corticosteroids, providing anti-inflammatory and anti-allergic effect. Due pronounced anti-inflammatory activity, reduces inflammation in the airways.
Thermopsis extract has expectorant action, exerting mild irritant effect on the gastric mucosa receptors, reflex increases the secretion of bronchial glands.
Sodium bicarbonate shifts the pH of the bronchial mucus in the alkaline side, reduces the viscosity of phlegm, stimulates the motor function of ciliary epithelium and bronchioles.
Pharmacokinetics
Data on the pharmacokinetics of the drug Broncho Codelac® not available.
Side effects
CNS: rarely - weakness, headache.
From the digestive system: rarely - diarrhea, dry mouth, constipation; Chronic administration of high doses - gastralgia, nausea, vomiting.
With the respiratory system: rarely - dry airway mucosa, rhinorrhea.
Other: rarely - dysuria, rash, allergic reactions.
Sale Properties
No prescription
Special conditions
Not combined with antitussive agents.
Indications
Respiratory system diseases with obstruction of sputum discharge:
- Acute and chronic bronchitis;
- Pneumonia;
- COPD;
- Bronchiectasis.
Contraindications
- Pregnancy;
- Lactation;
- Children up to age 12 years;
- Hypersensitivity to the drug.
Caution should be used in patients with hepatic and / or renal failure, gastric ulcer and duodenal ulcers, bronchial asthma
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