Bifiform is an immunobiological drug that belongs to the pharmacological group of eubiotics. This drug contains live lactic acid bacteria of 2 species, due to which it contributes to the normalization of the intestinal microflora and its functional activity.
Form of issue and composition
There are several medicinal forms of the drug - tablets, capsules and oily solution for oral administration. One capsule contains in its composition live lactic acid bacteria of 2 species - Bifidobacterium longum (10 7 bacterial cells) and Enterococcus faecium (10 7 bacterial cells). It also includes auxiliary substances, which include:
- The leaven is a dry lactic acid.
- Magnesium stearate.
- Gum.
- Lactulose.
- Anhydrous dextrose.
- Titanium dioxide.
- Polyethylene glycol.
- Yeast extract.
- Carob bean syrup.
Capsules are packaged in an aluminum tube of 20 or 30 pieces. One cardboard pack contains one tube and instructions for the use of the drug.
pharmachologic effect
Capsules Bifiform belong to the pharmacological group of medicines eubiotics. They contain live lactic acid bacteria of 2 species - Bifidobacterium longum and Enterococcus faecium. They are representatives of normal intestinal microflora and normally live on its mucous membrane. Lactic acid bacteria are necessary for the normal functioning of the intestine and have a number of biological effects, which include:
- The synthesis of lactose - disaccharide (milk sugar), which is a regulator of the digestive processes, with its sufficient amount in the intestine, the processes of decay and fermentation of organic compounds entering the food composition are suppressed.
- Regulation of acid-base balance in the lumen of the intestine.
- Suppression of pathogenic (pathogenic) and conditionally pathogenic microorganisms due to the synthesis of lactic acid.
- Strengthening the activity of oxidation-reduction processes in the intestine.
- Stimulation of the functional activity of immunity in the intestinal mucosa.
- Improved parietal and cavitary digestion - enzymatic systems of lactic acid bacteria promote the digestion of cellulose, a constituent of plant fiber, and carbohydrates, including disaccharides.
- The production of essential amino acids and vitamins (in particular, B vitamins) necessary for the body.
- The detoxification effect due to the adsorption of exogenous bacteria from the colonies (come from outside) and endogenous (formed in the intestines during digestion) toxins.
After taking the capsule, the bacteria pass through the upper sections of the gastrointestinal tract and stomach, in the lumen of the small intestine the capsule dissolves, providing the exit of the bacteria. In the intestines, lactic acid bacteria begin to multiply actively and colonize the mucous membrane. In this case, they do not penetrate into the blood. Excess amounts of bacteria are excreted from the intestine with feces.
Indications for use
The drug Bifiform is primarily indicated for the restoration of normal intestinal microflora, which has been altered due to various pathological processes:
- Dysbacteriosis - a change in normal microflora with a change in the ratio in favor of opportunistic bacteria. It develops after chronic infections, against the background of changes in the hormonal background, after prolonged antibiotic therapy, in which, together with pathogenic microorganisms, bacteria, representatives of normal microflora, are also destroyed.
- Acute intestinal infection or food intoxication caused by salmonella, shigella, Staphylococcus aureus, enteroviruses.
- Chronic pathology of the organs of the digestive system - inflammation of the stomach ( gastritis ), small and large intestines (enterocolitis), peptic ulcer of the stomach or duodenum, pathology of the hepatobiliary system (hepatitis, gallbladder inflammation), inflammation of the pancreas ( pancreatitis ).
- Acute, chronic diarrhea or constipation of various origins, including against the background of irritable bowel syndrome and prolonged stress.
- Allergy, which is caused by disturbances in the process of digestion and changes in the intestinal microflora.
- Malabsorption syndrome is an organic pathology with enzymatic deficiency and a violation of digestion and absorption of certain carbohydrates.
- In women in complex therapy of thrush (candidiasis) and dysbiosis (vaginosis) of the vagina.
- Complex preparation for surgical intervention on various organs, primarily the gastrointestinal tract.
Bifiform capsules are also used as an immunomodulating agent in children, who often get acute respiratory viral infections (colds more often 4 times a year). In women, they are used for chronic specific and nonspecific bacterial pathology of the reproductive system.
Contraindications
Absolute contraindication to the use of Bifiform is an individual intolerance or hypersensitivity to one of the components of the drug. With caution, it is used for individuals with lactase deficiency (a decrease in the production of the digestive enzyme that catalyzes the breakdown of lactose), since lactose is one of the auxiliary compounds of the drug.
Dosage and Administration
Capsules Bifiform taken inside regardless of the preliminary meal, drink a sufficient amount of liquid. Adults and children over 2 years of age average dosage is 1-2 capsules 2 times a day. The maximum daily dose for an adult is 4 capsules per day. Duration of the drug depends on the main pathology, with acute intestinal infection, food poisoning, Bifiform capsules are taken for 7-10 days. With different chronic pathology of the digestive system and dysbacteriosis - 10-20 days. Prophylactic reception is characterized by a decrease in the dose of the drug in half compared with the therapeutic dosage. For children under 2 years of age, a special dosage form Bifiform is used in the form of a syrup.
Side effects
The drug is well tolerated. When properly used according to the instructions in the recommended dosages, no side effects or adverse reactions were recorded.
special instructions
Before using Bifiform capsules, it is necessary to read the instructions. It is important to pay attention to such specific instructions regarding the use of the drug:
- In the case of an increase in the symptoms of the disease, worsening of the general condition, the appearance of blood veins in the stool for several days from the beginning of the drug, it is necessary to consult a doctor.
- Antibiotics inhibit the growth and reproduction of lactic acid bacteria, so when they are taken together, the dose of the drug is increased. With other pharmacological groups of drugs, Bifiform capsules do not interact.
- The drug can be used for pregnant, lactating women and children (in the form of a syrup, Bifiform can be used for children from birth).
- Simultaneous intake of fermented milk products and B vitamins stimulates growth, reproduction of lactic acid bacteria and the effect of Bifiform capsules as a whole.
- Receiving capsules Bifiform does not affect the speed of psychomotor reactions and the ability to concentrate.
- After taking the capsule, it is not advisable to drink with hot water, as this can lead to partial death of bacteria.
In the pharmacy network, the drug is dispensed without a prescription. If you have any questions or have any doubts about taking Bifiform capsules, you should consult your doctor.
Overdose
The main components of the drug do not have cumulative properties, they do not accumulate in the human body. When the dose and the amount of lactic acid bacteria in the intestine are exceeded, their excess is excreted from the body, so cases of overdose with Bifiform capsules are unknown.
Bifiform analogues
According to the species characteristics of the bacteria entering the preparation, Bifiform analogues are Acilactum, Lactobacterin, Linex, Probiophore, Bifidumbacterin.
Terms and conditions of storage
Shelf life of the drug from the time of manufacture is 2 years. Keep it in a dark, dry place inaccessible to children at an air temperature of no higher than 25 ° C.
