Composition
1 tab .:
- hyoscine butyl bromide 10 mg
Excipients: calcium hydrophosphate (anhydrous calcium hydrogenphosphate), dried corn starch, hydrolyzed potato starch (soluble starch), colloidal silicon dioxide, tartaric acid, stearic acid.
Shell composition: povidone (polyvinylpyrrolidone), sucrose, talc, acacia gum (gum arabic), titanium dioxide, macrogol 6000 (polyethylene glycol 6000), carnauba wax, white beeswax (white wax).
Pharmachologic effect
Farmgroup: m-holinoblokator.
Pharmaceutical action: Buscopan - a blocker of m-cholinergic receptors. It has an antispasmodic effect on the smooth muscles of internal organs, reduces the secretion of digestive glands. Does not penetrate through the BBB (since hyoscine butyl bromide is a quaternary ammonium derivative), therefore, there is no anticholinergic effect on the central nervous system.
Indications
- renal colic;
- biliary colic;
- spastic dyskinesia of the biliary tract and gallbladder;
- cholecystitis;
- intestinal colic;
- pilorospasm;
- gastric ulcer and duodenal ulcer in the acute phase (as part of complex therapy);
- Algomenorrhea.
Use during pregnancy and lactation
Use of the drug Buscopan during pregnancy and lactation (breastfeeding) is possible only if the intended benefit to the mother outweighs the potential risk to the fetus or infant.
Contraindications
- myasthenia gravis;
- megacolon;
- children's age up to 6 years;
- Hypersensitivity to the components of the drug Buscopan.
Side effects
Side effects associated with anticholinergic effects of the drug: dry mouth, dry skin, tachycardia; urine retention is possible (usually mild and resolved independently).
Allergic reactions: in rare cases - skin manifestations, anaphylaxis with episodes of shortness of breath.
Interaction
Buscopan® can enhance the anticholinergic effect of tricyclic antidepressants, antihistamines, quinidine, amantadine, disopyramide, anticholinergic drugs (for example, tiotropium bromide, ipratropium bromide).
The simultaneous use of Buscopan and dopamine antagonists (for example, metoclopramide) leads to a weakening of the effects on the gastrointestinal tract of both drugs.
Buscopan® can enhance tachycardia caused by beta-adrenomimetics.
How to take, the course of administration and dosage
Adults and children over 6 years old are prescribed orally for 1-2 tablets 3-5 times / day.
Tablets should be taken orally with water.
Overdose
Currently, cases of overdose of Buscopan® are not described, therefore the following symptoms and recommendations are theoretical.
Symptoms: possible anticholinergic effects - urinary retention, dry mouth, redness of the skin, tachycardia, depression of gastrointestinal motility, transient visual disturbances.
Treatment: shows the use of cholinomimetics. In case of glaucoma, pilocarpine is locally prescribed (in the form of eye drops). If necessary, prescribe cholinomimetics for systemic use (for example, administered in / m or / in neostigmine at a dose of 0.5-2.5 mg); cardiovascular complications are treated according to the usual therapeutic rules; conduct supportive and symptomatic therapy; with paralysis of the respiratory muscles - intubation and mechanical ventilation; during urinary retention - bladder catheterization.
Special instructions
With caution, the drug is prescribed for suspected intestinal obstruction (including pyloric stenosis), urinary tract obstruction (including prostate adenoma), with a tendency to tachyarrhythmia (including atrial fibrillation), angle-closure glaucoma .
Buscopan tablet contains 41.2 mg of sucrose. The maximum recommended daily dose contains 411.8 mg sucrose.
Release form
Buscopan tablets, coated (sugar) white, round, biconvex, with an almost imperceptible odor.
Storage conditions
Keep out of reach of children at a temperature not exceeding 25 ° C.
Shelf life
5 years.
Active substance
Hyoscine butyl bromide
Pharmacy sales terms
Over the counter
Amount in a package
20
Dosage Form
pills
