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Neobutine 100mg N10
Neobutine 100mg N10
Product Code: neobutine-100mg-n10 Obolenskoye

Neobutine 100mg N10

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1 tablet contains:

active substance: trimebutin maleate 100 mg;

excipients: lactose monohydrate 81.6 mg, corn starch 32 mg, colloidal silicon dioxide (Aerosil) 3.2 mg, magnesium stearate 3.2 mg.

Pharmachologic effect



- irritable bowel syndrome;

- postoperative paralytic intestinal obstruction.


- children's age up to 3 years (for this dosage form);

- pregnancy;

-  lactose intolerance , lactase deficiency, glucose-galactose malabsorption;

- Hypersensitivity to trimebutine maleate and other components that make up the drug.

Side effects

From the digestive system: dry mouth, unpleasant taste, diarrhea, dyspepsia, nausea, constipation.

From the nervous system: drowsiness, fatigue, dizziness,  headache , anxiety, a feeling of heat or cold.

Allergic reactions: skin rash.

Other: menstrual irregularities, painful enlargement of the mammary glands, urinary retention.


Drug interaction of the drug  Neobutin is  not described.

How to take, course of administration and dosage

The drug is taken orally, before meals.

Adults and children over 12 years of age are prescribed 100-200 mg 3 times / day.

To prevent relapse of irritable bowel syndrome after a course of treatment during the period of remission, it is recommended to continue taking the drug at a dose of 300 mg / day for 12 weeks.

Children aged 5-12 years are prescribed 50 mg 3 times / day, children aged 3-5 years - 25 mg 3 times / day.


To date, cases of an overdose of trimebutin have not been reported.

Special instructions

The course of treatment of the irritable bowel syndrome in the acute period at a dose of 600 mg / day for 4 weeks and the continuation of treatment after the course at a dose of 300 mg / day for 12 weeks avoids relapse.

Influence on the ability to drive vehicles and control mechanisms

The drug does not have a sedative effect, does not affect the speed of psychomotor reactions and can be used in people of various professions, including requiring increased attention and coordination of movements. However, given the possible side effects that may affect these abilities ( dizziness  and others), care should be taken when driving and engaging in other potentially dangerous activities.

Active substance


Sale terms

Without recipe

Dosage form


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