1 g of terbinafine hydrochloride 10 g
Antifungal drug for local use. It has a wide range of antifungal action.
Active against dermatophytes: Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton verrucosum, Trichophyton violaceum, Microsporum canis, Epidermophyton floccosum. In small concentrations, in addition to dermatophytes, terbinafine has a fungicidal effect against mold, yeast (mainly Candida albicans) and certain dimorphic fungi (Pityrospomm orbiculare). Activity against yeast fungi, depending on their species, can be fungicidal or fungistatic.
Terbinafine in a specific way changes the early stage of sterol biosynthesis occurring in fungi. This leads to a deficiency of ergosterol and intracellular accumulation of squalene, which causes the death of the fungal cell. The action of terbinafine is carried out by inhibiting the enzyme squalene epoxidase, located on the cell membrane of the fungus.
Termikon® has no effect on the isoenzymes of the cytochrome P450 system in humans and, accordingly, on the metabolism of hormones or other drugs.
- prevention and treatment of fungal infections of the skin, including mycoses of the feet (tinea pedis), inguinal athlete's (tinea cruris), fungal infections of the smooth skin of the body (tinea corporis) caused by dermatophytes;
- yeast infections of the skin (mainly caused by Candida albicans), in particular, diaper rash;
- versicolor versicolor (Pityriasis versicolor), caused by Pityrosporum orbiculare.
- hypersensitivity to the drug.
The drug should be used with caution in liver and / or kidney failure, alcoholism, inhibition of bone marrow hematopoiesis, tumors, metabolic diseases, occlusive vascular diseases of the extremities, in children under 12 years of age (lack of sufficient clinical experience).
Local reactions: redness, itching or burning sensation, allergic reactions are possible in places where the cream is applied.
Data on drug interactions Thermicon is not available.
How to take, the course of administration and dosage
Termikon® is prescribed externally for adults and children over 12 years old.
Before applying the cream must be cleaned and dried the affected areas. The cream is applied 1-2 times a day with a thin layer on the affected skin and surrounding areas, lightly rubbed.
For infections with diaper rash (under the mammary glands, in the interdigital spaces, between the buttocks, in the inguinal region), the places of application of the cream can be covered with gauze, especially at night.
The average duration of treatment for ringworm of the trunk, legs, feet - 1 time per day for 1 week; with candidiasis of the skin - 1-2 times / day for 1-2 weeks; with lichen colored - 1-2 times / day for 2 weeks.
Reducing the severity of clinical manifestations is usually observed in the first days of treatment. In the case of irregular treatment or its premature termination, there is a risk of re-infection. In case if after 1-2 weeks of treatment there are no signs of improvement, the diagnosis should be verified.
The dosage regimen for elderly patients is the same as for patients of other age groups.
No cases of drug overdose have been reported. If Termikon® is accidentally taken orally, you can expect the development of the same symptoms as with an overdose of tablets: headache, nausea, epigastric pain and dizziness.
Treatment: activated carbon, if necessary - symptomatic supportive therapy.
Cream for external use 1% white, uniform, with a weak specific odor.
Reducing the severity of clinical manifestations is usually observed in the first days of treatment. In the case of irregular treatment or its premature termination, there is a risk of recurrence of the infection.
Thermikon® is for external use only.
Avoid contact with eyes, as it may cause irritation. In case of accidental ingestion of the drug in the eyes, they should be immediately washed with running water, and if persistent irritation develops, consult a doctor.
With the development of allergic reactions necessary to cancel the drug.
Pharmacy sales terms
Over the counter
Amount in a package